en other Orginal research <div style="direction: rtl; text-align: left;"><strong><em>Background:</em></strong> Autism is a developmental disorder that impairs social relationships. Sleep disorders are one of the major problems of patients with autism spectrum disorders (ASD).<br> <strong><em>Objectives: </em></strong>Concerning the need to investigate problems and impairments caused by this disease, the present study aimed at determining the effect of an eight-week endurance training program plus Q10 supplementation on sleep quality in children with ASD in 2017.<br> <strong><em>Methods:</em></strong> The present double-blind study was performed on three experimental groups. Group 1 performed eight-week endurance training on a one-mile distance as brisk walking. Group 2 received 100 mg Q10 supplements daily and Group 3 underwent a combination of both interventions. Pre- and post-tests were performed to determine the sleep habits of the study subjects using the children&#39;s sleep habits questionnaire (CSHQ) by parents. Finally, the pre- and post-tests data were compared using the paired samples t-test.<br> <strong><em>Results</em></strong><strong>:</strong> A significant difference was observed between the pre- and post-test results in the mean total and eight subscales scores in the endurance training plus Q10 supplementation group (P <0.05). There was no significant difference between the pre- and post-test results in the sleep anxiety and sleep-disordered breathing subscales in the endurance training group and the sleep-disordered breathing subscale in the supplementation group.<br> <strong><em>Conclusion:</em></strong> According to the study results, it seems that the sleep of children with autism was improved by increased physical activity and Q10 supplementation.</div> endurance training, coenzyme q10, sleep quality, autism 56 61 http://nmcjournal.zums.ac.ir/browse.php?a_code=A-10-63-4&slc_lang=en&sid=1 Said Ahmadi s.a.v.ahmadi2014@gmail.com 10031947532846008313 10031947532846008313 No Cultural & student department, Zanjan university of medical sciences, Zanjan ,Iran MojganAlsadat Aghvamy aghvamym@zums.ac.ir 10031947532846008314 10031947532846008314 Yes Nursing and Midwifery faculty, Zanjan university of medical sciences, Zanjan, Iran Mahnaz Afshingoo zahram@zums.ac.ir 10031947532846008315 10031947532846008315 No Nursing and Midwifery faculty, Zanjan university of medical sciences, Zanjan, Iran