en Midwifery Orginal research <p><span style="line-height:2;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="unicode-bidi:embed"><span sans-serif=""><span style="color:#2980b9;"><b><i><span new="" roman="" times="">Background:</span></i></b></span> <span new="" roman="" times="">Epilepsy is the second most common and most dangerous neurological complication that can occur in a pregnant woman. Women with epilepsy (WWE) are at higher risk for miscarriage, prematurity, congenital anomalies, and low birth weight (LBW)</span><span new="" roman="" times="">. </span></span></span><br> <span style="unicode-bidi:embed"><span sans-serif=""><b><i><span new="" roman="" times=""><span style="color:#2980b9;">Objectives:</span> </span></i></b><span new="" roman="" times="">This study aimed to investigate the outcome of pregnancy in women with epilepsy.</span></span></span><br> <span new="" roman="" times=""><span style="color:#2980b9;"><b><i>Methods:</i></b></span><span style="color:black"> This descriptive study was conducted on 131 pregnant women with epilepsy who were referred to Ardabil Alavi Hospital from September 2019 to September 2021. Necessary information such as BMI, type of seizure, congenital malformation, treatment drug, and name of used drugs was collected through the patient&#39;s file by a checklist and then analyzed by using statistical methods in SPSS version 25.</span></span><br> <span style="unicode-bidi:embed"><span sans-serif=""><span style="color:#2980b9;"><b><i><span new="" roman="" times="">Results</span></i><span new="" roman="" times="">:</span></b></span><span new="" roman="" times=""><span style="color:#2980b9;"> </span>The frequency of neonate term birth was 83.21% and preterm birth was 16.79%. The frequency of babies with LBW was 22.85%. Most of women with 65.96% had cesarean delivery. More than 83% of seizures were generalized and 67.93% used mono-therapy. Only one fetus had malformation (0.76%). The most frequency among the patients receiving mono-therapy was related to the carbamazepine with 26.71% and among the women treated with multitherapy was related to Levetiracetam plus carbamazepine with 12.97%.</span></span></span><br> <span style="unicode-bidi:embed"><span sans-serif=""><span style="color:#2980b9;"><b><i><span new="" roman="" times="">Conclusion:</span></i></b></span><span new="" roman="" times=""> Pregnancies with epilepsy, even in cases with multidisciplinary care and no other risk factors, are still significantly associated with higher adverse outcomes.</span></span></span><br> <span style="unicode-bidi:embed"><span sans-serif=""><b><i><span style="font-family:"Times New Roman","serif""></span></i></b></span></span><br> &nbsp;</span></span></span></p> Epilepsy, Seizures, Pregnancy, Birth Defects, Malformation 1 7 http://nmcjournal.zums.ac.ir/browse.php?a_code=A-10-922-1&slc_lang=en&sid=1 Ghasem Fatahzadeh-Ardalani g.fattahzadeh2015@gmail.com 100319475328460013906 100319475328460013906 No Department of neurology, school of medicine, Ardabil University of Medical Sciences, Ardabil, Iran Roghayeh Darghahi r.darghahi@gmail.com 100319475328460013907 100319475328460013907 No Department of Gynecology and Obestetrics, school of medicine, Ardabil University of Medical Sciences, Ardabil, Iran Firouz Amani biostat.f@gmail.com 100319475328460013908 100319475328460013908 Yes Department of Community Medicine, school of medicine, Ardabil University of Medical Sciences, Ardabil, Iran Mohsen Peighambari M.Peighambari@gmail.com 100319475328460013909 0009-0006-3163-9589 No School of medicine, Ardabil University of Medical Sciences, Ardabil, Iran