en Nursing Orginal research <div style="text-align: justify;"><span style="line-height:2;"><span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="color:#2980b9;"><b>Background:</b></span> Pain and fatigue control after spinal surgery is a significant concern. Foot reflexology massage has a comprehensive effect on reducing pain and fatigue in patients.<br> <span style="color:#2980b9;"><b>Objectives:</b></span> This study aimed to determine the effect of foot reflexology massage on postoperative pain and fatigue trajectory after lumbar spine surgery.<br> <b><span style="color:#2980b9;">Methods:</span> </b>This randomized, parallel-group controlled trial was conducted on 68 patients undergoing lumbar spine surgery at Ayatollah Beheshti Hospital in Yasuj, Iran. Participants were randomly allocated to either the experimental or control group using a computer-generated randomization sequence. <span lang="EN-GB">The</span> experimental group received a standardized 30-minute foot reflexology massage session at least 4 hours after analgesic administration, while the control group received routine postoperative care without therapeutic massage. Data were collected using a demographic information form and a Visual Analog Scale (VAS). Pain, fatigue, and hemodynamic indicators were measured in both groups at 30, 60, 90 minutes, and 24 hours post intervention. Data were analyzed using Repeated Measures Analysis of Variance (ANOVA) in SPSS software, version 20.<br> <span style="color:#2980b9;"><b>Results:</b></span> The study results indicated that the experimental group had lower pain and fatigue scores compared with the control group (p < 0.001). Significant group, time, and group &times; time interaction effects were observed (p < 0.01, &eta;&sup2; = 0.07&ndash;0.15), while no significant differences were found at 24 hours. <span dir="RTL" lang="FA"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"></span></span><br> <b><span style="color:#2980b9;">Conclusion:</span> </b><span lang="EN-GB">Foot</span> reflexology massage may help reduce pain and fatigue in the early postoperative period after spinal surgery, but its effect does not seem to last up to 24 hours.<b> </b></span></span></span><br> &nbsp;</div> Foot, Massage, Pain, Fatigue, Reflexology 0 0 http://nmcjournal.zums.ac.ir/browse.php?a_code=A-10-1082-1&slc_lang=en&sid=1 SEYEDEH ESMAT HOSSEINI esmat.hosseini_110@yahoo.com 100319475328460014525 100319475328460014525 Yes Assistant professor, Nursing and Midwifery Care Research Center, Department of Medical- Surgical Nursing, Iran University of Medical Sciences, Tehran, Iran 1- Samaneh Lotfi mehr_sl90@yahoo.com 100319475328460014526 100319475328460014526 No PhD student in epidemiology at department of epidemiology and biostatistics, school of public health, Tehran University of Medical Sciences, Tehran, Iran