en Nursing Orginal research <div style="text-align: justify;"><span style="line-height:2;"><span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="background:white"><span style="color:#2980b9;"><strong>Background:</strong></span><span style="color:#0f1115"> Patients with heart failure (HF) experience worries that may affect their self‑efficacy, but this relationship remains underexplored in Iran.</span></span><br> <span style="background:white"><span style="color:#2980b9;"><strong>Objectives:</strong></span><span style="color:#0f1115"> This study aimed to determine the relationship between disease‑related worry and self‑efficacy, and to identify the independent socio‑demographic and clinical factors associated with worry among patients with HF.</span></span><br> <span style="background:white"><span style="color:#2980b9;"><strong>Methods:</strong> </span><span style="color:#0f1115">This study was conducted from July to August 2023 among 208 patients with HF admitted to Madani Hospital in Tabriz, selected by convenience sampling. Data were collected using the worry and cardiac self‑efficacy questionnaires. Descriptive statistics, Pearson&#39;s correlation coefficient, and multivariable linear regression were employed using SPSS version 24.</span></span><br> <span style="background:white"><span style="color:#2980b9;"><strong>Results:</strong> </span><span style="color:#0f1115">Participants were mainly male (57.7%), with a mean age of 59.73 years. The mean (SD) scores for worry and self‑efficacy were 85.76 (27.89) and 25.34 (8.99), respectively (higher worry score = lower worry). A significant positive correlation was observed between self‑efficacy and worry (r = 0.329, <i>p</i> < 0.001). Regression revealed that self‑efficacy (&beta; = 0.170, <i>p</i> = 0.023), university education (&beta; = 0.293, <i>p</i> = 0.011), below diploma (&beta; = 0.170, <i>p</i> = 0.044), and higher income (&beta; = 0.230, <i>p</i> = 0.011) were positively associated with worry scores. Conversely, hospital stay > 7 days (&beta; = ‑0.330, <i>p</i> = 0.001) and hospitalization frequency > 7 times (&beta; = ‑0.206, <i>p</i> = 0.020) were negatively associated (R&sup2; = 0.519, adjusted R&sup2; = 0.495, <i>p</i> < 0.001).</span></span><br> <span style="background:white"><span style="color:#2980b9;"><strong>Conclusion:</strong></span><span style="color:#0f1115"> Disease‑related worry in patients with HF was associated with self‑efficacy and several patient factors, highlighting potential targets for future interventional studies.</span></span></span></span></span><br> &nbsp;</div> Heart Failure, Self Efficacy, Disease Management, Patient Reported Outcome Measures, Health Knowledge Attitudes Practice 0 0 http://nmcjournal.zums.ac.ir/browse.php?a_code=A-10-973-3&slc_lang=en&sid=1 Mersal Mohammadnejad feizollahzadehh@tbzmed.ac.ir 100319475328460016890 0009-0002-8088-2201 No Department of Medical-Surgical Nursing, Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran Hossein Feizllahzadeh hosseinfeizalahzadeh@gmail.com 100319475328460016891 100319475328460016891 Yes Department of Medical-Surgical Nursing, Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran Azad Rahmani azad.rahmani@yahoo.com 100319475328460016892 100319475328460016892 No Department of Medical-Surgical Nursing, Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran