en Nursing Orginal research <div style="text-align: justify;"><span style="line-height:2;"><span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="color:#2980b9;"><strong><em>Background</em></strong><em>:</em></span> Blended learning is the thoughtful integration of online and face-to-face learning, which is widely accepted in nursing education.<br> <strong><em><span style="color:#2980b9;">Objectives:</span> </em></strong>Despite its importance and complicacy, few studies investigated this issue. This study aimed to extend knowledge regarding factors contributing to effective blended learning in nursing education.<br> <span style="color:#2980b9;"><strong><em>Methods:</em></strong></span> Following the Attride-Stirling content analysis method, we searched PubMed, Elsevier, Emerald, Science Direct, ProQuest, and Springer databases and national databases of SID and MagIran to identify relevant studies using various combinations of online, semi-online, hybrid, and mixed keywords from 2005 to 2018.<br> <span style="color:#2980b9;"><strong><em>Results</em>:</strong></span> Four main themes were identified, content, context, educational activities, and evaluation. Nine identified organizer themes were as follows: Content objectives, flexibility, control and evaluation, technological capabilities, support system, teaching activities, learning activities, performance feedback, and evaluation methods. Finally, 23 basic themes codes were obtained as factors that should be embedded in the online nursing curriculum.<br> <span style="color:#2980b9;"><strong><em>Conclusion:</em></strong> </span>Blended learning is a rational and flexible method to improve the educational performance of nursing students. However, it should be based on need assessment, appropriate planning and execution, and evaluation and feedback.</span></span></span></div> Content Analysis, Hybrid Curriculum, Nursing 45 52 http://nmcjournal.zums.ac.ir/browse.php?a_code=A-10-754-2&slc_lang=en&sid=1 Ali Toghyani alitoghiyany@yahoo.com 100319475328460014230 100319475328460014230 No Department of Curriculum planning, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran Jahanbakhsh Rahmani rahmani@khuisf.ac.ir 100319475328460014231 100319475328460014231 Yes Assistant, Department of educational science and psychology, Isfahan(Khorasgan) Branch, Islamic Azad University, Isfahan, Iran Shayesteh Salehi salehi@nm.mui.ac.ir 100319475328460014232 100319475328460014232 No Community Health Research Center, Islamic Azad University, Isfahan (Khorasgan) branch, Isfahan, Iran Marzieh Adel Mehraban adel@nm.mui.ac.ir 100319475328460014233 100319475328460014233 No Associate Professor of Nursing School of Nursing and Midwifery, Nursing Management Department, Iran University of Medical Sciences