Preventive Care in Nursing and Midwifery Journal
Zanjan University of Medical Science
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Volume 11, Issue 4 (12-2021)
PCNM 2021, 11(4): 1-7 |
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Ahanghar H, Heydari A, Tahrekhani M, Mohammadi M, Abdi M, Jalilvand A. Association of Troponin-I Level on Admission with 6-month Clinical Consequences in Acute Coronary Syndrome Patients: A Preventive Approach in Patient Care. PCNM 2021; 11 (4) :1-7
URL: http://nmcjournal.zums.ac.ir/article-1-692-en.html
URL: http://nmcjournal.zums.ac.ir/article-1-692-en.html
Hassan Ahanghar 
, Atefeh Heydari , Mehran Tahrekhani , Maryam Mohammadi , Mohammad Abdi , Ahmad Jalilvand *
, Atefeh Heydari , Mehran Tahrekhani , Maryam Mohammadi , Mohammad Abdi , Ahmad Jalilvand *
Associated Professor, Pathologist, Department of Pathology, Mousavi hospital, school of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran , Ahmad.jalilvand@zums.ac.ir
Abstract: (7163 Views)
Background: Cardiovascular diseases are the leading cause of mortality worldwide. Therefore, it is important to predict the future consequences of the disease in patients who have recovered.
Objectives: We sought to determine the relationship between troponin-I level and 6-month clinical consequences (i.e., re-infarction, death, re-angiography and coronary artery bypass grafting) in patients with acute coronary syndrome (ACS).
Methods: This prospective cross-sectional study was performed among 60 patients with ACS admitted to Ayatollah Mousavi Hospital in Zanjan, Iran. The participants were chosen using the convenience sampling method. Troponin-I level in these patients was initially evaluated. Afterwards, they were followed up for six months in terms of clinical consequences. A checklist was prepared to collect the required data. The receiver operating characteristic (ROC) analysis was conducted to determine the predictive power of high-sensitivity troponin I for the mentioned consequences. Iodine index was calculated to determine the cutoff point for this enzyme in order to predict the consequences.
Results: In general, 66.2% of the participants were male and the mean age was 60.46 ± 12.78 years. We found that 21.2% of the participants experienced one of the four clinical consequences in the follow-up period of 6 months. The sub-curved surface was calculated to be 0.705 for the prediction of consequences. The cutoff point for the prediction of consequences was 32.5; the negative predictive value for the cutoff point was 32.5, which was equal to 89.8%.
Conclusion: Troponin-I has an acceptable predictive power to identify 6-month consequences of ACS. Moreover, considering the negative predictive value of troponin-I, it is recommended to use this biomarker in patients with ACS. In addition, healthcare providers should pay more attention to the follow-up of patients after discharge and design preventive programs.
Objectives: We sought to determine the relationship between troponin-I level and 6-month clinical consequences (i.e., re-infarction, death, re-angiography and coronary artery bypass grafting) in patients with acute coronary syndrome (ACS).
Methods: This prospective cross-sectional study was performed among 60 patients with ACS admitted to Ayatollah Mousavi Hospital in Zanjan, Iran. The participants were chosen using the convenience sampling method. Troponin-I level in these patients was initially evaluated. Afterwards, they were followed up for six months in terms of clinical consequences. A checklist was prepared to collect the required data. The receiver operating characteristic (ROC) analysis was conducted to determine the predictive power of high-sensitivity troponin I for the mentioned consequences. Iodine index was calculated to determine the cutoff point for this enzyme in order to predict the consequences.
Results: In general, 66.2% of the participants were male and the mean age was 60.46 ± 12.78 years. We found that 21.2% of the participants experienced one of the four clinical consequences in the follow-up period of 6 months. The sub-curved surface was calculated to be 0.705 for the prediction of consequences. The cutoff point for the prediction of consequences was 32.5; the negative predictive value for the cutoff point was 32.5, which was equal to 89.8%.
Conclusion: Troponin-I has an acceptable predictive power to identify 6-month consequences of ACS. Moreover, considering the negative predictive value of troponin-I, it is recommended to use this biomarker in patients with ACS. In addition, healthcare providers should pay more attention to the follow-up of patients after discharge and design preventive programs.
Type of Study: Orginal research |
Subject:
other
Received: 2020/11/2 | Accepted: 2021/02/28 | Published: 2021/02/28
Received: 2020/11/2 | Accepted: 2021/02/28 | Published: 2021/02/28
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