Preventive Care in Nursing and Midwifery Journal
Volume 16, Issue 3 (7-2026)
Prev Care Nurs Midwifery J 2026, 16(3): 0-0 |
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li L, Cao X, Luan J, Fu , J. Nursing Management of Continuous Autologous Bile Perfusion in a Patient with Malignant Obstructive Jaundice: A Case Report. Prev Care Nurs Midwifery J 2026; 16 (3)
URL: http://nmcjournal.zums.ac.ir/article-1-1039-en.html
URL: http://nmcjournal.zums.ac.ir/article-1-1039-en.html
Hepatobiliary and Pancreatic SurgeryDepartment, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Abstract: (3 Views)
Background: Prolonged percutaneous transhepatic cholangial drainage (PTCD) in malignant obstructive jaundice (MOJ) causes fluid and electrolyte deficits. Continuous autologous bile perfusion (CABP) offers a physiological alternative, but standardized nursing protocols are lacking.
Objectives: To describe the preoperative nursing management of CABP in a patient with MOJ, with a focus on protocol implementation and monitoring of patient tolerance and safety.
Methods: This case report describes a 58-year-old female with MOJ receiving preoperative PTCD, enteral nutrition, and continuous autologous bile perfusion via a closed‑loop system. Nursing responsibilities included: (1) daily bile quality and circuit patency monitoring; (2) aseptic technique during collection and reinfusion; (3) adverse event surveillance; and (4) documentation of nutritional, hepatic, and complication outcomes. Tolerance and safety were assessed at least twice per shift.
Results: After 12 days of combined nutritional support and CABP, total bilirubin fell from 258.9 to 83.5 μmol/L, albumin rose from 31.8 to 33.0 g/L, and weight stabilized at 48.5 kg. No perfusion‑related adverse events occurred. The patient underwent radical resection and was discharged. At the July 2025 follow‑up, she was independent and asymptomatic.
Conclusion: Structured CABP with multidisciplinary nursing may support nutritional and hepatic recovery in PTCD‑treated MOJ patients. Larger cohort studies are needed.
Objectives: To describe the preoperative nursing management of CABP in a patient with MOJ, with a focus on protocol implementation and monitoring of patient tolerance and safety.
Methods: This case report describes a 58-year-old female with MOJ receiving preoperative PTCD, enteral nutrition, and continuous autologous bile perfusion via a closed‑loop system. Nursing responsibilities included: (1) daily bile quality and circuit patency monitoring; (2) aseptic technique during collection and reinfusion; (3) adverse event surveillance; and (4) documentation of nutritional, hepatic, and complication outcomes. Tolerance and safety were assessed at least twice per shift.
Results: After 12 days of combined nutritional support and CABP, total bilirubin fell from 258.9 to 83.5 μmol/L, albumin rose from 31.8 to 33.0 g/L, and weight stabilized at 48.5 kg. No perfusion‑related adverse events occurred. The patient underwent radical resection and was discharged. At the July 2025 follow‑up, she was independent and asymptomatic.
Conclusion: Structured CABP with multidisciplinary nursing may support nutritional and hepatic recovery in PTCD‑treated MOJ patients. Larger cohort studies are needed.
Type of Study: case report |
Subject:
Nursing
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