Preventive Care in Nursing and Midwifery Journal
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Volume 10, Issue 2 (8-2020)
PCNM 2020, 10(2): 48-54 |
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Bayat F, Rezaee Moradali M, Roozbahani S, Towfighi S, Shami M. Prevalence of Hypothyroidism and Pregnancy Outcomes in Women Referred to Ayatollah Mousavi Hospital in Zanjan in 2018-2019. PCNM 2020; 10 (2) :48-54
URL: http://nmcjournal.zums.ac.ir/article-1-685-en.html
URL: http://nmcjournal.zums.ac.ir/article-1-685-en.html
master student, Tehran university of medical sciences, school of nursing and midwifery, Tehran, Iran , mshami@razi.tums.ac.ir
Abstract: (6274 Views)
Background: Hypothyroidism is common during pregnancy. This disorder is associated with adverse maternal and neonatal outcomes.
Objectives: The study of the prevalence and different consequences of hypothyroidism in pregnancy in each region is the special importance in determining prevention and management strategies. Therefore, the aim of this study was to determine the prevalence of hypothyroidism and pregnancy outcomes in women referred to Ayatollah Mousavi Hospital in Zanjan.
Methods: This cross-sectional-analytical study was performed on all pregnant women who gave birth in Ayatollah Mousavi Hospital in Zanjan in 2018-2019. Data were collected through census and using Chi-square, Fisher's exact and independent t-tests and with SPSS software version 22, pregnancy outcomes between the two groups were calculated.
Results: The prevalence of hypothyroidism in pregnant women in the present study was estimated at 8.59%. Hypothyroidism was found to double the chance of gestational diabetes (p<0.02) (CI=1.1-3.8). The rate of cesarean delivery was significantly higher in patients (p<0.001). The rate of fetal heart rate drop, placental abruption, and placental adhesion was higher in the affected group, but this difference was not significant (p>0.05). There was no significant difference between the two groups in terms of preeclampsia, preterm delivery, first minute Apgar score, height, weight and head circumference of the newborn (p>0.05).
Conclusion: Considering the adverse maternal and neonatal outcomes of hypothyroidism, it seems that more clinical studies in this field are needed to manage and evaluate the outcomes in pregnant women with hypothyroidism
Objectives: The study of the prevalence and different consequences of hypothyroidism in pregnancy in each region is the special importance in determining prevention and management strategies. Therefore, the aim of this study was to determine the prevalence of hypothyroidism and pregnancy outcomes in women referred to Ayatollah Mousavi Hospital in Zanjan.
Methods: This cross-sectional-analytical study was performed on all pregnant women who gave birth in Ayatollah Mousavi Hospital in Zanjan in 2018-2019. Data were collected through census and using Chi-square, Fisher's exact and independent t-tests and with SPSS software version 22, pregnancy outcomes between the two groups were calculated.
Results: The prevalence of hypothyroidism in pregnant women in the present study was estimated at 8.59%. Hypothyroidism was found to double the chance of gestational diabetes (p<0.02) (CI=1.1-3.8). The rate of cesarean delivery was significantly higher in patients (p<0.001). The rate of fetal heart rate drop, placental abruption, and placental adhesion was higher in the affected group, but this difference was not significant (p>0.05). There was no significant difference between the two groups in terms of preeclampsia, preterm delivery, first minute Apgar score, height, weight and head circumference of the newborn (p>0.05).
Conclusion: Considering the adverse maternal and neonatal outcomes of hypothyroidism, it seems that more clinical studies in this field are needed to manage and evaluate the outcomes in pregnant women with hypothyroidism
Type of Study: Orginal research |
Subject:
Midwifery
Received: 2020/10/4 | Accepted: 2020/08/31 | Published: 2020/08/31
Received: 2020/10/4 | Accepted: 2020/08/31 | Published: 2020/08/31
References
1. Dashe JS, Bloom SL, Spong CY, Hoffman BL. Williams obstetrics. 25th ed. New York: McGraw Hill Professional; 2018.
2. Ezzeddine D, Ezzeddine D, Hamadi C, et al. Prevalence and correlation of hypothyroidism with pregnancy outcomes among lebanese women. J Endocr Soc. 2017; 1(5): 415- 22. [Crossref]
3. Nazarpour S, Tehrani FR, Rahmati M, et al. Validation of Billewicz scoring system for detection of overt hypothyroidism during pregnancy. Int J Endocrinol Metab. 2018; 16(3). [Crossref]
4. Momtazan M, Mohammadi MJ, Tabahfar R, et al. Risk factors accelerating hypothyroidism in pregnant women referred to health centers in Abadan, Iran. Data Brief. 2017; 14: 15- 19. [Crossref]
5. Etemadi A, Amouzegar A, Mehran L, et al. Isolated Hypothyroxinemia in Iranian Pregnant Women, the Role of Iodine Deficiency: A Population-Based Cross-Sectional Study. Thyroid. 2020; 30(2): 262- 9. [Crossref]
6. Azizi F, Delshad MH, Amouzegar A, Mehran L, Mirmiran P. Prevention of iodine-deficiency induced goiter and brain damage in the islamic republic of Iran. Iran J Endocrinol Metab. 2014; 15(5): 411- 29.
7. Springer D, Jiskra J, Limanova Z, Zima T, Potlukova E. Thyroid in pregnancy: From physiology to screening. Crit Rev in Clin Lab Sci. 2017; 54(2): 102- 16. [Crossref]
8. López-Muñoz E, Ibarra-Avalos JA, Chan-Verdugo RG, Mateos-Sánchez L, Sánchez-Rodríguez O. Prevalence of hypothyroidism during pregnancy in a highly specialised referral centre in Mexico. J Obstet Gynaecol. 2016; 36(8): 1069- 75. [Crossref]
9. Dulek H, Vural F, Aka N, Zengin S. The prevalence of thyroid dysfunction and its relationship with perinatal outcomes in pregnant women in the third trimester. North clin Istanb. 2019; 6(3): 267- 72.
10. Dhanwal DK, Bajaj S, Rajput R, et al. Prevalence of hypothyroidism in pregnancy: An epidemiological study from 11 cities in 9 states of India. Indian J Endocrinol Metab. 2016; 20(3): 387- 90. [Crossref]
11. Kiran Z, Sheikh A, Malik S, et al. Maternal characteristics and outcomes affected by hypothyroidism during pregnancy (maternal hypothyroidism on pregnancy outcomes, MHPO-1). BMC Pregnancy childbirth. 2019; 19(1): 476. [Crossref]
12. Lotfalizadeh M, Ghomian N, Mohammad Nezhad M. Prevalence and Complications of Hypothyroidism in Pregnancy. Iran J Obstet, Gynecol Infertil. 2017; 20(8): 1- 5. [In Persian]
13. Borzouei Sh, Goodarzi MT, Biglari M, Nazari F, Shivapour Z. The Prevalence of Thyroid Disorders in Pregnant Women of Hamadan. Avicenna J Nurs Midwifery Care. 2019; 27(1): 11- 7. [In Persian] [Crossref]
14. Ajmani SN, Aggarwal D, Bhatia P, Sharma M, Sarabhai V, Paul M. Prevalence of overt and subclinical thyroid dysfunction among pregnant women and its effect on maternal and fetal outcome. J Obstet Gynecol India. 2014; 64(2): 105- 10. [Crossref]
15. Mannisto T, Vaarasmaki M, Pouta A, et al. Thyroid dysfunction and autoantibodies during pregnancy as predictive factors of pregnancy complications and maternal morbidity in later life. J Clin Endocrinol Metab. 2010; 95(3): 1084- 94. [Crossref]
16. Männistö T, Vääräsmäki M, Pouta A, et al. Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study. J Clin Endocrinol Metab. 2009; 94(3): 772- 79. [Crossref]
17. Turunen S, Vääräsmäki M, Männistö T, et al. Pregnancy and perinatal outcome among hypothyroid mothers: a population-based cohort study. Thyroid. 2019; 29(1): 135- 41. [Crossref]
18. Naderi T, Honarvar Z, Bahrampor A, Yosefzadeh G. The prevalence of hypothyroidism based on risk factors in pregnant women referred to Shahid Dadbin Clinic, Kerman, Iran. J Kerman Univ Med Sci. 2012; 19(3): 225-32. [In Persian]
19. Klein RZ, Haddow JE, Falx JD, et al. Prevalence of thyroid deficiency in pregnant women. Clin Endocrinol. 1991; 35(1): 41- 6. [Crossref]
20. Cleary-Goldman J, Malone FD, Lambert-Messerlian G, et al. Maternal thyroid hypofunction and pregnancy outcome. Obstet Gynecol. 2008; 112(1): 85-92. [Crossref]
21. Cakmak BD, Turker UA, Temur M, Ustunyurt E. Pregnancy outcomes of antibody negative and untreated subclinical hypothyroidism. J Obstet Gynaecol Res. 2019; 45(4): 810- 16. [Crossref]
22. Shinohara DR, Santos Th, de Carvalho HC, et al. Pregnancy complications associated with maternal hypothyroidism: a systematic review. Obstet Gynecol Survey. 2018; 73(4): 219- 30. [Crossref]
23. Chen L-M, Du W-J, Dai J, et al. Effects of subclinical hypothyroidism on maternal and perinatal outcomes during pregnancy: a single-center cohort study of a Chinese population. PLoS One. 2014; 9(10): e109364. [Crossref]
24. Stohl HE, Ouzounian J, Rick A-M, Hueppchen NA, Bienstock JL. Thyroid disease and gestational diabetes mellitus (GDM): is there a connection? J Matern Fetal Neonatal Med. 2013; 26(11): 1139- 42. [Crossref]
25. Lee SY, Cabral HJ, Aschengrau A, Pearce EN. Associations Between Maternal Thyroid Function in Pregnancy and Obstetric and Perinatal Outcomes. J Clin Endocrinol Metab. 2020; 105(5): e2015- e23. [Crossref]
26. Luisi S, Giorgi M, Riggi S, Messina G, Severi FM. Neonatal outcome in pregnancy hypotiroidee women. Gynecol Endocrinol. 2020; 36(9): 772-75 [Crossref]
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