Preventive Care in Nursing and Midwifery Journal
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Volume 13, Issue 4 (10-2023)
PCNM 2023, 13(4): 61-70 |
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Ethics code: IR.SBMU.SME.REC.1399.066
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Rezaei N, Shakerian S. A case-control study on risk factors of breast cancer in Damghan, Iran. PCNM 2023; 13 (4) :61-70
URL: http://nmcjournal.zums.ac.ir/article-1-877-en.html
URL: http://nmcjournal.zums.ac.ir/article-1-877-en.html
Department of Community- Based Education of Health Sciences, Virtual School of Medical Education and Management, Shahid Beheshti University of Medical Sciences, Tehran, Iran , sarehshakerian@gmail.com
Abstract: (921 Views)
Background: The available information denotes the increased annual occurrence of breast cancer in Iranian women and the decreased age of developing this disease.
Objectives: The present study aimed to assess risk factors for breast cancer in Iranian women.
Methods: The present research was conducted in a hospital-based case-control study on 46 cases and 43 controls from March 2019 to March 2020 in Damghan. The interview was conducted to collect data by a predesigned questionnaire consisting of socio-demographic variables, nutrition and physical activity, and a checklist for fertility, and care items. Descriptive and analytical statistics, including the chi-square and logistic regression models, were used to analyze data by SPSS- ver16.
Results: The findings showed that out of 46 cases, only 6 (6.7%) were detected by self-examination and two cases by health workers. The average age of breast cancer in the case group was 53.28 ± 10.4 years. The results showed significant association in many terms of education level, employment status, physical activity, nutrition and fertility factors (OR≤1, P-value≤0.05). Based on the determination coefficient obtained considering the mentioned variables, at minimum, 68.2%, and at maximum, 91% of the changes in the likelihood of developing the risk of breast cancer can be explained.
Conclusion: Consistent with most studies, the findings of the current research showed a significant association with the developing risk of breast cancer. Considering that most factors identified in the present study are preventable, there should be effective interventions to control the disease and its complications in society.
Objectives: The present study aimed to assess risk factors for breast cancer in Iranian women.
Methods: The present research was conducted in a hospital-based case-control study on 46 cases and 43 controls from March 2019 to March 2020 in Damghan. The interview was conducted to collect data by a predesigned questionnaire consisting of socio-demographic variables, nutrition and physical activity, and a checklist for fertility, and care items. Descriptive and analytical statistics, including the chi-square and logistic regression models, were used to analyze data by SPSS- ver16.
Results: The findings showed that out of 46 cases, only 6 (6.7%) were detected by self-examination and two cases by health workers. The average age of breast cancer in the case group was 53.28 ± 10.4 years. The results showed significant association in many terms of education level, employment status, physical activity, nutrition and fertility factors (OR≤1, P-value≤0.05). Based on the determination coefficient obtained considering the mentioned variables, at minimum, 68.2%, and at maximum, 91% of the changes in the likelihood of developing the risk of breast cancer can be explained.
Conclusion: Consistent with most studies, the findings of the current research showed a significant association with the developing risk of breast cancer. Considering that most factors identified in the present study are preventable, there should be effective interventions to control the disease and its complications in society.
Type of Study: Orginal research |
Subject:
Midwifery
Received: 2023/05/22 | Accepted: 2023/10/2 | Published: 2023/10/2
Received: 2023/05/22 | Accepted: 2023/10/2 | Published: 2023/10/2
References
1. World Health Organization. Cancer: Early diagnosis and screening [Internet]. 2020 [Retrived 6 Aug 2020]. Available at: https://www.who.int/ cancer/prevention/diagnosis-screening/en
2. Kavya N, Sriraam N, Usha N, Hiremath B, Suresh A, Sharath D, et al. Breast cancer lesion detection from the cranial-caudal view of mammogram images using statistical and texture features extraction. International Journal of Biomedical and Clinical Engineering (IJBCE). 2020;9(1):16-32. [Crossref]
3. Ansari H, Mohammadi M, Mohammadi Y, Hashemi SM, Ghavami N, Zare F, et al. Assessment of socio-economic and menstrual-reproductive factors related to estimated risk of affecting breast cancer in the Iranian woman. Koomesh. 2018; 20(3).
4. Kazeminia M, Salari N, Hosseinian-Far A, Akbari H, Bazrafshan MR, Mohammadi M. The prevalence of breast cancer in Iranian women: a systematic review and meta-analysis. Indian Journal of Gynecologic Oncology. 2022;20(1):14. [Crossref]
5. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2021 May;71(3):209-49. [Crossref]
6. Haghighat S, Omidi Z, Ghanbari-Motlagh A. Trend of Breast Cancer Incidence in Iran During A Fifteen-Year Interval According To National Cancer Registry Reports. Iranian Journal of Breast Diseases. 2022 Jul 10;15(2):4-17. [Crossref]
7. Aryannejad A, Saeedi Moghaddam S, Mashinchi B, Tabary M, Rezaei N, Shahin S, Rezaei N, Naghavi M, Larijani B, Farzadfar F. National and subnational burden of female and male breast cancer and risk factors in Iran from 1990 to 2019: results from the Global Burden of Disease study 2019. Breast Cancer Research. 2023 Dec;25(1):1-26.
8. Malekzadeh MM, Peykani S, Amani O. Comparative study of quality of life in women survived with those suffered from breast cancer while under chemotherapy. 2017.
9. Feng Y, Spezia M, Huang S, Yuan C, Zeng Z, Zhang L, et al. Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis. Genes & diseases. 2018;5(2):77-106. [Crossref]
10. Bui OT, Tran HT, Nguyen SM, Dao TV, Bui QV, Pham AT, Shrubsole MJ, Cai Q, Ye F, Zheng W, Luu HN. Menstrual and Reproductive Factors in Association With Breast Cancer Risk in Vietnamese Women: A Case-Control Study. Cancer Control. 2022 Nov 10;29:10732748221140206. [Crossref]
11. Lantz PM, House JS, Lepkowski JM, Williams DR, Mero RP, Chen J. Socioeconomic factors, health behaviors, and mortality: results from a nationally representative prospective study of US adults. Jama. 1998;279(21):1703-8. [Crossref]
12. Koosha M, Haghighat S, Karampoor R, Shekarbeygi A, Bahrami A, Tafazzoli-Harandi H, et al. Evaluation of Socio-economic Status and its Impact on coping Behavior of Patients with Breast Cancer. Iranian Quarterly Journal of Breast Disease. 2017;9(4):15-25. [Crossref]
13. Noh E, Khang YH. Occupational inequalities in mortality in South Korea using nationally representative mortality follow-up data from the late 2000s and after. (2021). [Crossref]
14. Taheri M, Tavakol M, Akbari ME, Mohammadbeigi A, Abbasi M. Socio-Economic Status Inequity in self rated health in patients with breast cancer. Open Access Macedonian Journal of Medical Sciences. 2019 Jan 1;7(1):152. [Crossref]
15. Shafiei S, Yazdani S, Jadidfard M-P, Zafarmand AH. Measurement components of socioeconomic status in health-related studies in Iran. BMC research Notes. 2019;12(1):1-11. [Crossref]
16. Ayoubi SS, Yaghoubi Z, Pahlavani N, Philippou E, MalekAhmadi M, Esmaily H, Ranjbar G, Amini M, Nematy M, Norouzy A. Developed and validated food frequency questionnaires in Iran: A systematic literature review. J Res Med Sci. 2021 Jul 31;26:50. doi: 10.4103/jrms.JRMS_652_20. PMID: 34484382; PMCID: PMC8384004. [Crossref]
17. Sadeghi S, Montazeri V, Zamora-Ros R, Biparva P, Sabour S, Pirouzpanah S. Food frequency questionnaire is a valid assessment tool of quercetin and kaempferol intake in Iranian breast cancer patients according to plasma biomarkers. Nutrition Research. 2021 Sep 1;93:1-4. [Crossref]
18. Akram M, Iqbal M, Daniyal M, Khan AU. Awareness and current knowledge of breast cancer. Biological research. 2017;50(1):1-23. [Crossref]
19. Sun Y-S, Zhao Z, Yang Z-N, Xu F, Lu H-J, Zhu Z-Y, et al. Risk factors and preventions of breast cancer. International journal of biological sciences. 2017;13(11):1387. [Crossref]
20. Asgarian F, Mirzaei M, Asgarian S, Jazayeri M. Epidemiology of Breast Cancer and the Age Distribution of Patients over a Period of Ten Years. ijbd 2016
21. 9 (1) :31-36Nafissi N, Khayamzadeh M, Zeinali Z, Pazooki D, Hosseini M, Akbari ME. Epidemiology and histopathology of breast cancer in Iran versus other Middle Eastern countries. Middle East Journal of Cancer. 2018;9(3):243-51.
22. Nafissi N, Khayamzadeh M, Zeinali Z, Pazooki D, Hosseini M, Akbari ME. Epidemiology and histopathology of breast cancer in Iran versus other Middle Eastern countries. Middle East Journal of Cancer. 2018;9(3):243-51.
23. Taheri M, Tavakol M, Akbari ME, Anoshirvani AA, Aghabozorgi R, Almasi-Hashiani A, Abbasi M. Socioeconomic inequalities in metastasis, recurrence, stage and grade of breast cancer: a hospital-based retrospective cohort study. Journal of preventive medicine and hygiene. 2019 Sep;60(3):E262.
24. Josette Sin, Y. C., Holly Ching, Y. L., Amy, C., Hang Mei, L., Eliza, F., Sian, G., & Polly, C. (2014). Socioeconomic Disparity in Breast Cancer Detection in Hong Kong - A High Income City: Retrospective Epidemiological Study Using the Breast Cancer Registry. Journal pone. [Crossref]
25. Eaker, S., Halmina, M., Bellocco, R., Bergkvist, L., Ahlgren, J., Holmberg, L. & Lambe, M. (2009). Uppsala/Orebro Breast Cancer Group. Social differences in breast cancer survival in relation to patient management within a National Health Care System (Sweden). Int J Cancer, 124(1), 180-187. http://dx.doi.org/10.1002/ijc.23875 [Crossref]
26. Fenga C. Occupational exposure and risk of breast cancer. Biomedical reports. 2016 Mar 1;4(3):282-92. [Crossref]
27. Terry MB, Michels KB, Brody JG, Byrne C, Chen S, Jerry DJ, Malecki K, Martin MB, Miller RL, Neuhausen SL, Silk K. Environmental exposures during windows of susceptibility for breast cancer: a framework for prevention research. Breast Cancer Research. 2019 Dec;21(1):1-6. [Crossref]
28. Laden F, Hunter DJ. Environmental risk factors and female breast cancer. Annual review of public health. 1998;19:101. [Crossref]
29. Cade J, Thomas E, Vail A. Case-control study of breast cancer in south east England: nutritional factors. Journal of Epidemiology & Community Health. 1998;52(2):105-10. [Crossref]
30. Knekt P, Järvinen R, Seppänen R, Pukkala E, Aromaa A. Intake of dairy products and the risk of breast cancer. British Journal of Cancer. 1996;73(5):687-91. [Crossref]
31. Kour A, Sharma S, Sambyal V, Guleria K, Singh NR, Uppal MS, Manjari M, Sudan M, Kukreja S. Risk factor analysis for breast cancer in premenopausal and postmenopausal women of Punjab, India. Asian Pacific Journal of Cancer Prevention: APJCP. 2019;20(11):3299. [Crossref]
32. Kaaks R, Van Noord PA, Den Tonkelaar I, Peeters PH, Riboli E, Grobbee DE. Breast‐cancer incidence in relation to height, weight and body‐fat distribution in the Dutch "DOM" cohort. International journal of cancer. 1998;76(5):647-51.https://doi.org/10.1002/(SICI)1097-0215(19980529)76:5<647::AID-IJC6>3.0.CO;2-Q [Crossref]
33. Titus-Ernstoff L, Longnecker MP, Newcomb PA, Dain B, Greenberg ER, Mittendorf R, et al. Menstrual factors in relation to breast cancer risk. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 998;7(9):783-9.
34. Wu H-C, Yang H-I, Lin P-H, Chen C-J, Santella RM, Terry MB. Reproductive and environmental exposures and the breast cancer risk in Taiwanese women. Scientific Reports. 2021;11(1):1-7. [Crossref]
35. Park B, Hopper JL, Win AK, Dowty JG, Sung HK, Ahn C, et al. Reproductive factors as risk modifiers of breast cancer in BRCA mutation carriers and high-risk non-carriers. Oncotarget. 2017;8(60):102110. [Crossref]
36. Huber D, Seitz S, Kast K, Emons G, Ortmann O. Use of oral contraceptives in BRCA mutation carriers and risk for ovarian and breast cancer: a systematic review. Archives of gynecology and obstetrics. 2020;301(4):875-84. [Crossref]
37. Kanadys W, Barańska A, Malm M, Błaszczuk A, Polz-Dacewicz M, Janiszewska M, et al. Use of oral contraceptives as a potential risk factor for breast cancer: A systematic review and meta-analysis of case-control studies up to 2010. International journal of environmental research and public health. 2021; 18(9): 4638.
37. Marcus PM, Newman B, Moorman PG, Millikan RC, Baird DD, Qaqish B, et al. Physical activity at age 12 and adult breast cancer risk (United States). Cancer Causes & Control. 1999; 10(4): 293-302.https://doi.org/10.1023/A:1008971417282 [Crossref]
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